MSC-Derived Exosomes Protect Auditory Hair Cells From Neomycin-Induced Damage Via Autophagy Regulation

    January 2024 in “ Biological Research
    Huan Liu, Huijuan Kuang, Yiru Wang, Lili Bao, Wanxin Cao, Yu Lu, Meihao Qi, Renfeng Wang, Xianghua Yang, Qingyuan Ye, Feng Ding, Lili Ren, Siying Liu, Furong Ma, Shiyu Liu
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    Studysummary This study found that mesenchymal stem cell-derived exosomes reduced hearing and hair cell loss caused by neomycin in experimental models by modulating autophagy, which promoted cell survival and lowered oxidative stress and apoptosis, indicating potential for deafness treatment.
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