8 citations
,
June 2021 in “International Journal of Molecular Sciences” In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.
November 2025 in “British Journal of Pharmacology” This study found that inositol hexaphosphate significantly reduced hearing threshold shifts and outer hair cell loss in various sensorineural hearing loss mouse models, suggesting potential for otoprotective use.
January 2024 in “Biological Research” This study found that mesenchymal stem cell-derived exosomes reduced hearing and hair cell loss caused by neomycin in experimental models by modulating autophagy, which promoted cell survival and lowered oxidative stress and apoptosis, indicating potential for deafness treatment.
April 2023 in “Research Square (Research Square)” Exosomes protect ear hair cells from damage by controlling cell waste removal, potentially helping treat hearing loss.
8 citations
,
January 2005 in “Acta Oto-Laryngologica” This case study reports that ciclosporin effectively managed symptoms in a patient with steroid-dependent sudden sensorineural hearing loss, allowing discontinuation of corticosteroids and confirming remission through audiometry.