Morphogenetic Mechanisms in the Cyclic Regeneration of Hair Follicles and Deer Antlers from Stem Cells

    January 2013 in “ BioMed research international ”
    Chunyi Li, A. J. Pearson, Chris McMahon
    Image of study
    TLDR Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
    In the 2013 study, researchers compared hair follicles (HFs) and antler units (AUs), finding that despite their differences in size and visibility, both share similarities in their regeneration processes. Both HFs and AUs have permanent and cyclic components, rely on stem-cell-based organogenesis, and undergo cyclic regeneration. Stem cells are located in the permanent part of each organ, while the growth centers are in the temporary part. The regeneration of both HFs and AUs depends on epithelial-mesenchymal interactions, which are facilitated by the destruction of the cyclic part to bring reactive cells close to the stem cell niche. Additionally, both organ developments are influenced by similar hormonal (testosterone) and growth factors (IGF1). The study suggests that researchers in both HF and AU biology could benefit from the findings of this comparison.
    Discuss this study in the Community →

    Research cited in this study

    17 / 17 results

    Related Community Posts Join

    6 / 1000+ results

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 7 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community find a cure for this shit already

      in Chat  207 upvotes 4 years ago
      Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.

      community Best Microneedle Lengths To Stimulate Stem Cells

      in Microneedling  18 upvotes 1 year ago
      Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

    Related Research

    2 / 2 results