January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a formulated polyherbal shampoo demonstrated effective antifungal properties against dandruff-causing fungi, with smooth, intact hair cuticles after treatment, suggesting it may serve as a safe, natural alternative for managing dandruff.
6 citations
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May 2022 in “Research and reports in urology” This study found that Caesalpinia bonduc seed extracts significantly reduced prostate weight and improved prostate tissue morphology in Wistar rats with testosterone-induced benign prostatic hyperplasia.
2 citations
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November 2009 in “DSpace (Federal University of Santa Catarina)” Brunfelsia uniflora has good antioxidant properties and moderate antibacterial activity.
March 2022 in “INDIAN JOURNAL OF APPLIED RESEARCH” This study found that the formulated shampoo using alcoholic extracts of Hibiscus rosa-sinensis demonstrated antimicrobial and antifungal activity and met all standard evaluation criteria, offering a potentially safer alternative to synthetic shampoos without harmful preservatives like paraben.
May 2023 in “International Journal of Trichology” In this study, 70% of female androgenetic alopecia patients who did not respond to standard minoxidil experienced clinical improvement after switching to a propylene glycol-free, witch hazel-based 5% minoxidil sulfate solution, with the treatment also being well-tolerated.
September 2020 in “Pharmauho/Pharmauho : Jurnal Farmasi, Sains dan Kesehatan” This study concluded that hair tonic formulated with galangal rhizome and Aloe vera extract was stable according to the Indonesian National Standard, showing consistent organoleptic, pH, and viscosity characteristics after stability testing.
September 2022 in “Pharmacy Today”
June 1992 in “Inpharma Weekly” Patch testing with different solvents helps find the right minoxidil formulation for those with scalp allergies.
April 2020 in “Dermatology and therapy” In this study, the novel 5% minoxidil formulation significantly increased scalp hydration and decreased redness in Indian men with androgenetic alopecia compared to alcohol-based formulations.
1 citations
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October 2015 in “The Pharma Innovation Journal” This study found that the optimal method to introduce Saw Palmetto extract into emulsion bases for androgenic alopecia treatment involves mixing it with 48% ethanol at the end of the formulation process.
20 citations
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October 2018 in “Physics and chemistry of liquids” This study found that minoxidil exhibits preferential solvation by water in both water-rich and ethanol-rich solvent mixtures.
This study compared the safety and effectiveness of 5% cetosomal minoxidil to 5% alcohol-based minoxidil in Indian men with androgenetic alopecia, finding that cetosomal minoxidil had improved safety and similar efficacy, making it a potentially better option for those sensitive to alcohol-based formulations.
21 citations
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January 2017 in “MethodsX” This study found that methanol is more effective than isopropanol at removing external cortisol from grizzly bear hair and suggests that the choice of solvent can influence hair cortisol concentration results.
25 citations
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November 1994 in “The Journal of Dermatologic Surgery and Oncology” In this study, acetone was not superior to other degreasers for enhancing the efficacy of trichloroacetic acid peels, and its higher flammability suggests using alternative degreasers to reduce workplace hazards.
November 2023 in “Journal of Drugs in Dermatology” In this study, stabilized super-oxidized hypochlorous acid was used during and after hair transplant surgeries, reportedly reducing erythema and pruritus in over half of patients, with high compliance and no tissue necrosis observed.
September 2023 in “Journal of the American Academy of Dermatology”
September 2007 in “Dermatologic Surgery” This study found that using 3% hydrogen peroxide for surgical wound care during hair restoration surgery did not significantly impact the survival rate of hair grafts compared to normal saline.
4 citations
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January 2018 in “Research journal of pharmacy and technology” This study found that Wera leaf extract, particularly its n-hexane fraction, significantly stimulated hair growth, suggesting its potential as an antialopecia treatment.
February 2024 in “Jurnal Kesehatan Yamasi Makassar” This study in South Sulawesi Province developed a shampoo using ethanol extract from Pondoh salak fruit peel, which met physical stability tests and demonstrated strong inhibitory effects against Staphylococcus epidermidis and Candida albicans, with formulations ranging from 10% to 20% concentrations.
July 2024 in “International Journal of Advanced Research in Science Communication and Technology” This study explored the antibacterial and wound-healing effects of an 80% methanol extract from Hibiscus micranthus leaves, finding it effective against several bacterial strains and beneficial for wound healing in rats.
24 citations
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April 2011 in “Journal of Chemical & Engineering Data” This study measured the solubility of minoxidil in various solvents, finding the highest solubility in methanol and lowest in water, with solubility correlating to temperature.
1 citations
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February 2023 in “Pharmaceutics” This study suggests that UVA-responsive nanocapsules may provide an effective method for skin antisepsis by releasing ethanol and reducing microorganisms within hair follicles on ex vivo porcine ear skin.
February 2024 in “PubMed” This study reported that minoxidil lotions produced using a propylene glycol-free base, Aloplus Total, demonstrated high minoxidil solubility and maintained chemical and physical stability for over 180 days, suggesting suitability for enhanced topical treatments of androgenetic alopecia.
October 2017 in “Our Dermatology Online” This study reports that while DCP had similar treatment efficacy in propylene glycol and isopropanol for alopecia areata, the formulation in isopropanol was better tolerated.
118 citations
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.
13 citations
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September 2017 in “International Journal of Cosmetic Science” This study found that waving virgin human hair with thioglycerol at pH 9.0 using ammonia solution caused less damage than using thioglycolic acid, while maintaining good waving efficiency.
September 2019 in “Journal of Investigative Dermatology” This study found that a new formulation using short chain esters and ethanol can selectively deliver hydrogen peroxide to hair follicles during epilation, causing follicular damage without affecting epidermal keratinocytes.
January 2025 in “Regenerative Biomaterials” In this study, a new pH-responsive hydrogel composed of polyvinyl alcohol and boric acid was found to release salvianolic acid B effectively, reducing excessive scar formation and enhancing tissue regeneration during early-stage wound healing.
January 2021 in “Indonesian Journal on Medical Science” This study concluded that a hair tonic combining aloe vera and celery extracts can be formulated, with formula 1 meeting the stability requirements best over a month.
4 citations
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December 2007 in “Dermatologic Surgery” This study found that using 3% hydrogen peroxide for surgical wound care during hair restoration did not significantly affect the survival rate of hair grafts compared to normal saline.