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This review discusses the roles of metabolism, reactive oxygen species, intracellular pH, and cell morphology in influencing cell fate decisions during stem cell differentiation but reports no new experimental results.

This article provides an overview of the biological process of skin wound healing, detailing the roles of keratinocytes, dermal cells, and trichogenesis without presenting new experimental results.

This study mapped the genome-wide epigenetic landscape in secondary hair follicle stem cells of goats, revealing distinct histone modification signatures associated with cashmere fiber cycling during different stages of hair growth.

The researchers proposed that an epigenetic change in brain androgen receptors caused by finasteride could lead to post finasteride syndrome, while trazodone might reverse this effect by altering the epigenetic expression related to erection and libido.

This review discusses the roles of epigenetic and environmental factors in the regeneration of skin appendages and highlights potential therapeutic approaches for conditions like alopecia.

This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.

This review discusses current research on epigenetic changes in autoimmune skin diseases like vitiligo and alopecia areata, noting that the field is still developing and lacks extensive analysis.

This article reviews how epigenetic modifications, particularly DNA methylation, histone modification, and non-coding RNA pathways, affect the development of skin diseases, suggesting potential for personalized treatments that target these changes.

This study found that cultured foreskin is not suitable for studying H2A.J-related tissue changes during radiation-induced dermatitis due to existing high H2A.J expression and cytokine secretion even without irradiation.

This study found that Myc activation in epidermal stem cells leads to chromatin modifications that promote stem cell exit and differentiation, which can be influenced by HDAC inhibitors like trichostatin A.

This study found that in adult mouse skin, reduced levels of histone H3 K4/K9/K27me3 during hair follicle stem cell quiescence are linked to proper tissue homeostasis.

In this study, overexpression of secretory phospholipase A2 Group-IIA in transgenic mice led to depletion of hair follicle stem cells and increased differentiation, linked to changes in histone modifications.

This study found that DNA methylation and histone modification status were altered in peripheral blood mononuclear cells of patients with alopecia areata, suggesting these changes may contribute to the disease's pathological immune responses.

This study found that in live mouse epidermal stem cells, chromatin compaction is heterogenous and reflects differentiation status, with transcriptional changes largely preceding chromatin rearrangements during differentiation.

This study found that dermal papilla cells exhibit stage-dependent variation in histone methylation during the hair follicle cycle and display distinct chromatin marker expression when transitioning to in vitro culture.

In this review, researchers discuss the role of epigenetic modifications in epidermal stem cells' decline during skin aging and identify potential interventions targeting these disruptions, suggesting significant possibilities for antiaging strategies and dermatological treatments.

This study found that sustained intracellular acidosis in mice was associated with shortened lifespan, early aging signs, and impaired autophagy.

This study found that stem cells derived from spinal and bulbar muscular atrophy patients exhibited reduced androgen receptor levels and HDAC6, providing potential insights into the disease mechanism for future therapies.

This review discusses the impact of endocrine-disrupting chemicals on pediatric health, linking them to various disorders, and calls for improved biomonitoring strategies and precautionary policies.

In a dermal Gorab knockout mouse model, this study found that Gorab mutations increase P53 protein accumulation and disrupt extracellular matrix expression, contributing to accelerated skin aging and suggesting a pathway involving epigenetic regulation.

This review discusses epigenetic mechanisms in tissue repair across species and summarizes recent CRISPR-based technologies as promising tools for studying and enhancing tissue regeneration, but reports no new experimental results.

This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.

This study reveals that epidermal stem cell differentiation in mice involves dynamic transcriptional changes, with Keratin-10 transcription preceding gradual chromatin compaction shifts associated with differentiation.

This review discusses the role of epigenetics in colorectal cancer and explains how changes like DNA methylation impact tumor development, but it reports no new results.

The study demonstrates that acetate treatment may alleviate PCOS-associated depression in rats by reducing neuroinflammation and modifying epigenetic changes in the brain.

Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.

This review discusses the role of enhancers and super-enhancers in tissue-specific gene regulation and cancer development, and it reports no new experimental results.

This study used proteomics to identify various proteins in human hair, which may help develop novel biomarkers for hair health, disease, and aging.

This review discusses the biochemical and biological functions of histone demethylases and their potential involvement in human diseases, including cancer, but reports no new findings.

This study found that reducing HDAC1 activity in the skin of mice led to defects in hair follicle structure and pigmentation, highlighting HDAC's role in skin and hair maintenance.