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30-60 / 382 resultsresearch Exosomes derived from dermal papilla cells mediate hair follicle stem cells proliferation through the Wnt3a/β-catenin signaling pathway
This study demonstrates that exosomes derived from dermal papilla cells (DPC-Exos) can enhance the proliferation of hair follicle stem cells (HFSCs) through the Wnt3a/β-catenin signaling pathway. By using cell co-culture systems and manipulating the expression of Wnt3a, researchers found that DPC-ExosOE-Wnt3a upregulated the mRNA expression of downstream genes in the Wnt/β-catenin pathway, increased PCNA protein content, and promoted HFSC proliferation while inhibiting apoptosis. These findings provide new insights into the molecular mechanisms of hair growth and potential treatments for hair loss in humans, as well as applications in the breeding of Angora rabbits.
research Exosomes for Regeneration, Rejuvenation, and Repair
Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
research 1494 Dual effects of HA-iMSC-exosomes in human follicle dermal papilla cells (HFDPC) on androgenic alopecia in vitro model
Exosomes from certain stem cells can fight hair loss by promoting hair growth and maintaining the growth phase of hair.
research Exosomes and Hair Restoration
Exosomes, tiny cell-released particles, may help hair growth, but their exact role is unclear, they're not FDA-approved, and their unregulated use can cause side effects.
research MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation
Exosomes protect ear hair cells from damage by controlling cell waste removal, potentially helping treat hearing loss.
research Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1
Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
research Exosomes from Hair Follicle Epidermal Neural Crest Stem Cells Promote Acellular Nerve Allografts to Bridge Rat Facial Nerve Defects
research Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling
Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
research Human Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Papilla Cell
HHORSC exosomes and PL improve hair growth treatment outcomes.
research Garlic Exosomes Promote Hair Growth Through the Wnt/β-catenin Pathway and Growth Factors
Garlic can help hair grow by activating certain growth pathways, and it works whether you eat it or apply it to your scalp.
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration
Fat stem cell particles help regrow hair.
research Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition From Telogen to Anagen Phase
research Mesenchymal stem cell‐derived exosomes for organ development and cell‐free therapy
The document reviewed the role of mesenchymal stem cell-derived exosomes (MSC-Exos) in organ development and their potential as cell-free therapeutic agents. It highlighted that MSC-Exos can mediate intercellular communication during the organogenesis of structures like the salivary gland, tooth, hair follicle, and kidney. The review also discussed the therapeutic benefits of MSC-Exos in conditions such as ischemic heart disease, cutaneous wound healing, and COVID-19. The authors provided a critical analysis of exosome biogenesis, molecular composition, isolation, and characterization, and emphasized the reparative potential and mechanisms of action of MSC-Exos, while also addressing major challenges in the field.
research Extracellular Vesicles Including Exosomes for Hair Follicle Regeneration
Extracellular vesicles, including exosomes from certain cells, can stimulate hair growth.
research Dermal papilla cell-derived exosomes promote hair follicle regeneration during wound healing by activating Wnt/β‐catenin signaling pathway
Tiny particles from skin cells can help grow new hair by activating a specific growth signal during skin healing.
research MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation
Tiny particles from stem cells can help protect ear cells from antibiotic damage by helping cells remove damaged parts.
research Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/β-Catenin Pathway
Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
research Isolation of sensory hair cell specific exosomes in human perilymph
research Fibroblast‐derived growth factors and exosomes as cosmeceuticals
Fibroblast-derived growth factors and exosomes have been used in skincare for over 20 years to improve aged and photodamaged skin. Exosomes, tiny extracellular vesicles from fibroblasts, mesenchymal stem cells, or adipose-derived stem cells, show potential in wound healing, skin rejuvenation, skin disease, pigmentation, and hair growth. This review discusses the collection, characterization, and formulation of fibroblast-derived exosomes for skincare. A product containing 98 billion exosomes per mL used twice daily for 12 weeks significantly improved skin aging parameters such as wrinkles, roughness, sagging, and laxity. Active exosomes, along with growth factors, may enhance aging skin if their biological activity remains stable in formulations.
research Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway
research Isolation of sensory hair cell specific exosomes in human perilymph
research Chitosan Hydrogel Dressing Loaded with Adipose Mesenchymal Stem Cell-Derived Exosomes Promotes Skin Full-Thickness Wound Repair
The new Exo/Gel dressing with stem cell-derived particles helps skin wounds heal faster.
research Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser
White hair patch repigmented and hair regrew in a balding patient after treatment with exosomes and laser.
research Regenerative potential and clinical application of mesenchymal stem cell-derived exosomes (review)
This review highlights the regenerative potential and clinical applications of mesenchymal stem cell (MSC)-derived exosomes, emphasizing their role in transferring signaling and regulatory molecules between cells. The study analyzes the molecular profile and biological properties of exosomes from various MSC sources and their clinical use in treating COVID-19, alopecia, skin aging, and osteoarthritis. The review underscores the importance of understanding the unique properties of MSCs from different tissues to develop effective exosome-based therapies, marking a significant advancement in regenerative medicine.
research From Hair to Colon: Hair Follicle-Derived MSCs Alleviate Pyroptosis in DSS-Induced Ulcerative Colitis by Releasing Exosomes in a Paracrine Manner
research “Why we should treat COVID-19 Long Hauler Syndromes with Convalescent Plasma; Contained Suppressive Exosomes are likely COVID antigen-specific”
The document suggests using convalescent plasma to treat COVID-19 Long Hauler Syndromes because it may contain beneficial elements that target the virus.