Mesenchymal Stem Cells and Cell-Free Preparations for Treating Atopic Dermatitis

    January 2022 in “ Biocell ”
    Trinidad Montero‐Vílchez, Manuel Sánchez‐Díaz, CAROLINA MONTERO-VILCHEZ, Álvaro Sierra-Sánchez, Salvador Arias‐Santiago
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    TLDR Mesenchymal stem cells and their secretions might help treat chronic skin inflammation in atopic dermatitis.
    Atopic dermatitis (AD) is a chronic skin inflammatory disease that can be difficult to treat in some patients. The paper discusses the potential of using Mesenchymal stem cells (MSCs) and cell-free preparations like MSCs-Conditioned Medium (CM) and MSCs-exosomes as treatments for AD. MSCs are non-hematopoietic multipotent adult progenitor cells with the ability to modulate the immune response and self-regenerate to repair tissue damage. MSCs-CM and MSCs-exosomes contain molecules secreted by stem cells that could also be beneficial for treating AD. The paper reviews the current development of these potential treatments.
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