Exosomes: Historical Evolution and Emerging Roles in Dermatology

Exosomes, once thought to be cellular waste, are now recognized as crucial in intercellular communication and hold promise in dermatology for diagnostics and treatment, particularly in conditions like hair loss. They can modulate immune responses, influence pigmentation, and promote hair growth, with stem cell-derived exosomes showing potential in hair regeneration. Exosomes can be delivered topically or via injections, with transdermal methods enhancing efficacy. Despite their potential, challenges such as standardization, safety, and large-scale production need to be addressed for clinical use. Continued research is essential to fully realize their therapeutic potential.