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    Did you mean Epidermal Growth Factor?
    Glossary Epidermal Growth Factor

    stimulates cell growth and healing in skin and hair

    Epidermal Growth Factor (EGF) is a protein that stimulates cell growth, proliferation, and differentiation by binding to its receptor, EGFR. It plays a crucial role in the healing of wounds and the regeneration of skin and hair follicles. EGF is often used in skincare products to promote skin repair and reduce signs of aging.

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    1. Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. PubMed · 1997 · 107 citations
    2. Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation Journal of Dermatological Science · 2013 · 97 citations
    3. Epidermal Growth Factor as a Biologic Switch in Hair Growth Cycle 2003 · 94 citations
    4. Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management Dermatology research and practice · 2014 · 68 citations
    5. 2,3,7,8‐Tetrachlorodibenzo‐<i>p</i>‐dioxin causes an increase in protein kinases growth hepatic associated with epidermal factor receptor in the plasma membrane Journal of Biochemical Toxicology · 1988 · 60 citations
    6. Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro Archives of Dermatological Research · 1987 · 58 citations
    7. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling Cellular physiology and biochemistry · 2016 · 43 citations
    8. The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth? Dermatology Online Journal · 2009 · 39 citations
    9. Fibroblast growth factor and epidermal growth factor in hair development 1993 · 39 citations
    10. Epidermal growth factor promotes proliferation of dermal papilla cells via Notch signaling pathway Biochimie · 2016 · 36 citations
    11. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression Stem Cell Research & Therapy · 2016 · 24 citations
    12. Cutaneous Lesions in the Rat Following Administration of an Irreversible Inhibitor of erbB Receptors, Including the Epidermal Growth Factor Receptor Toxicologic Pathology · 2008 · 21 citations
    13. Epidermal growth factor in aesthetics and regenerative medicine: Systematic review Journal of Cutaneous and Aesthetic Surgery · 2021 · 12 citations
    14. Epidermal growth factor, innovation and safety Medicina Clínica (english Edition) · 2015 · 10 citations
    15. Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells Archives of Dermatological Research · 1990 · 10 citations
    16. Epidermal growth factor and fibroblast growth factor accelerate proliferation of human hair bulb papilla cells and root sheath tibroblasts cultured in vitro British Journal of Dermatology · 1987 · 9 citations
    17. More is not always better in hair growth factors. epidermal growth factor: hair growth factor involved in alopecia areata pathogenesis International Journal of Trichology · 2020 · 4 citations
    18. Epidermal growth factor promotes mesenchymal stem cell-mediated wound healing and hair follicle regeneration. PubMed · 2017 · 4 citations
    19. Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways International Journal of Molecular Sciences · 2024 · 3 citations
    20. The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth? - eScholarship Dermatology Online Journal · 2009
    21. Epidermal Growth Factor Receptor Regulates Skin Nerve Outgrowth and Branching Journal of Investigative Dermatology · 2009
    22. Effects of Epidermal Growth Factor and Transforming Growth Factor on Cultured Hair Follicle Cells from Human Scalp Skin research · 1994
    23. Safety Profile of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Disproportionality Analysis of FDA Adverse Event Reporting System Scientific Reports · 2020 · 58 citations
    24. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    25. Taiwanese Dermatological Association consensus for the prevention and management of epidermal growth factor receptor tyrosine kinase inhibitor-related skin toxicities Journal of the Formosan Medical Association · 2017 · 22 citations
    26. The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors Postępy Dermatologii i Alergologii · 2017 · 18 citations
    27. Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo Frontiers in Pharmacology · 2020 · 7 citations
    28. Epidermal growth factor, but not cortisol, suppresses fibre growth in cultured follicles Livestock Production Science · 2003 · 4 citations
    29. 546 Epidermal growth factor receptor as a key regulator of the immune privilege Journal of Investigative Dermatology · 2022
    30. Association between epidermal growth factor and epidermal growth factor receptor gene polymorphisms and susceptibility to alopecia areata in Korean population Journal of the American Academy of Dermatology · 2013