20 citations,
March 2021 in “Drug design, development and therapy” Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.
[object Object]
The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.
3 citations,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
11 citations,
August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
101 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
11 citations,
August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
3 citations,
September 2022 in “Molecules” Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
22 citations,
July 2019 in “PLOS ONE” Skin lymphatic vessels are essential for hair growth.
21 citations,
January 2018 in “The Korean Journal of Physiology and Pharmacology” Modified stem cells from umbilical cord blood can make hair grow faster.
1 citations,
September 2020 in “Journal of Dermatological Science” The gene LRRC15 is more active in balding areas of the scalp compared to non-balding areas.
November 2022 in “Bioengineering” The method can test hair growth products using a lab-made hair-like structure that responds to known treatments.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
29 citations,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
9 citations,
August 2018 in “Biomedical dermatology” A peptide called DPS-1 helps human scalp cells grow and stimulates hair growth in mice.
11 citations,
October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
3 citations,
January 2017 in “Yonsei Medical Journal” Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.
January 2022 in “Stem cell biology and regenerative medicine” New biofabrication technologies could lead to treatments for hair loss.
10 citations,
April 2013 in “Journal of Investigative Dermatology” Scientists created a model using sheep cells to study hair root formation, which can test how different substances affect hair growth.
2 citations,
November 2008 in “Medical Hypotheses” VEGF and its receptor might cause hair loss.
March 2024 in “Bioactive Materials” New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
May 2024 in “Molecules/Molecules online/Molecules annual” Plant extracts can help prevent hair loss and promote hair growth.
4 citations,
May 2012 in “Tissue Engineering and Regenerative Medicine” Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
9 citations,
August 2015 in “Tissue Engineering and Regenerative Medicine” Human skin cell byproducts can potentially be used to treat hair loss and promote hair growth.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
12 citations,
February 1999 in “British Journal of Dermatology” Minoxidil increased small openings in blood vessel walls near growing hair in rats.
[object Object]
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
March 2023 in “International Journal of bioprinting” Zinc/silicon-infused hydrogel helps regenerate hair follicles.