research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
Creating fully functional artificial skin for chronic wounds is still very challenging.
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30 / 1000+ resultsresearch In Vivo Expansion and Regeneration of Full-Thickness Functional Skin with an Autologous Homologous Skin Construct: Clinical Proof of Concept for Chronic Wound Healing
A new skin treatment using a patient's own cells healed chronic wounds effectively and was preferred over traditional grafts.
research Gene Therapy to Enhance Angiogenesis in Chronic Wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Extracellular Vesicles from Hair Follicle-Derived Mesenchymal Stromal Cells: Isolation, Characterization, and Therapeutic Potential for Chronic Wound Healing
Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.
research Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study
Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
research Modulation of Macrophage Functions by ECM-Inspired Wound Dressings – A Promising Therapeutic Approach for Chronic Wounds
ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
research Defining Chronic Wound Types in Recessive Dystrophic Epidermolysis Bullosa Patients for Clinical Outcome Assessment
The conclusion is that differentiating wound types in RDEB patients is important for clinical trials and understanding the disease.
research Soy Protein/Beta-Chitin Sponge-Like Scaffolds Laden With Human Mesenchymal Stromal Cells Promote Diabetic Chronic Wound Healing
Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.
research Platelet-Rich Plasma and Platelet-Rich Fibrin Clot Dressing in Chronic Wound Management: Two Case Reports
PRP and PRF can effectively heal chronic wounds.
research Successful Allogeneic Epidermal Grafting of Chronic Recessive Dystrophic Epidermolysis Bullosa Wounds from Hematopoietic Cell Donors in the Outpatient Setting
Skin grafts from related donors significantly healed chronic wounds in patients with a severe skin condition over a year.
research Rothmund-Thomson Syndrome Type 2 – A Rare Cause of Chronic Wounds
Rothmund-Thomson syndrome type 2 can cause chronic, poorly healing wounds.
research Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects
Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.
research Nanotechnology Approaches in Chronic Wound Healing
Nanotechnology shows promise for better chronic wound healing but needs more research.
research Wearable Bioelectronics for Chronic Wound Management
Wearable bioelectronics show promise for improving chronic wound care.
research A Compositionally Synergistic Approach for the Development of a Multifunctional Bilayer Scaffold with Antibacterial Property for Infected and Chronic Wounds
The developed scaffold effectively treats chronic wounds by promoting healing and preventing infection.
research Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers
Innovative biomaterials show promise in healing chronic diabetic foot ulcers.
research Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review
Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.
research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research Epithelial-To-Mesenchymal Transition in Cutaneous Wound Healing: Where We Are and Where We Are Heading
The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
research Reflections on How Wound Healing-Promoting Effects of the Hair Follicle Can Be Translated into Clinical Practice
Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
research The Wound Microbiome
The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.
research The Use of Platelet-Rich Plasma in Wound Healing and Vitiligo: A Systematic Review and Meta-Analysis
Platelet-rich plasma (PRP) may improve healing in chronic wounds and vitiligo and promote hair regrowth, but more research is needed.
research Orchestration of Mesenchymal Stem/Stromal Cells and Inflammation During Wound Healing
Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
research Use of Phytotherapeutics, Low Power Laser, and Ozone for Biting Wound in Dog
A dog's chronic bite wound healed successfully using a mix of herbal gel, low power laser, and ozone therapy.
research Cellular Therapeutics and Immunotherapies in Wound Healing – On the Pulse of Time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research Cutaneous Response to Injury and Wound Healing
Wound healing involves three phases and various cells and factors, with scars typically forming in adults. Chronic wounds can occur due to various issues, and abnormal scarring can lead to hypertrophic or keloid scars. Emerging research areas include the role of proteins, microRNAs, macrophage manipulation, and stem cell treatment.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Wound Healing and the Use of Medicinal Plants
Some medicinal plants can help heal wounds and may lead to new treatments.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.