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    Glossary Chronic Wounds

    injuries that don't heal within a typical 3-month period

    Chronic wounds, also known as non-healing or persistent wounds, are injuries to the skin that fail to progress through the normal stages of healing within a predictable timeframe, typically around 3 months. These wounds can result from various underlying conditions such as diabetes, poor circulation, or prolonged pressure, and often require specialized medical treatment to promote healing and prevent complications like infection.

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    Research 30 of 1000+

    1. Cellular and molecular mechanisms of repair in acute and chronic wound healing British Journal of Dermatology · 2015 · 908 citations
    2. Macrophage Related Chronic Inflammation in Non-Healing Wounds Frontiers in Immunology · 2021 · 228 citations
    3. A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro? Cells · 2020 · 133 citations
    4. In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing International Wound Journal · 2019 · 38 citations
    5. Gene therapy to enhance angiogenesis in chronic wounds Molecular Therapy — Nucleic Acids · 2022 · 36 citations
    6. Biomembrane-Based Nanostructure- and Microstructure-Loaded Hydrogels for Promoting Chronic Wound Healing International Journal of Nanomedicine · 2023 · 24 citations
    7. Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing Stem cell research & therapy · 2022 · 22 citations
    8. Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study Stem Cells International · 2020 · 14 citations
    9. Pectin Nanoparticle-Loaded Soft Coral Nephthea sp. Extract as In Situ Gel Enhances Chronic Wound Healing: In Vitro, In Vivo, and In Silico Studies Pharmaceuticals · 2023 · 10 citations
    10. Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds Biological Chemistry · 2021 · 9 citations
    11. Triple-layered core-shell fiber dressings with enduring platelet conservation and sustained growth factor release abilities for chronic wound healing Regenerative Biomaterials · 2024 · 7 citations
    12. Transplantation of autologous single hair units heals chronic wounds in autosomal recessive dystrophic epidermolysis bullosa: A proof-of-concept study Journal of Tissue Viability · 2020 · 7 citations
    13. Plasma Medicine: Innovative Methods of Diagnosis and Treatment of Chronic Wounds and Oncological Diseases SSP Modern Pharmacy and Medicine · 2025 · 5 citations
    14. RETRACTED: Clinical observation of ultraviolet therapy combined with autologous platelet‐rich plasma in the treatment of chronic refractory wounds International Wound Journal · 2024 · 2 citations
    15. Platelet-rich plasma treatment for chronic wounds: A case report and literature review World Journal of Clinical Cases · 2024 · 2 citations
    16. 572 Defining chronic wound types in recessive dystrophic epidermolysis bullosa patients for clinical outcome assessment Journal of Investigative Dermatology · 2018 · 2 citations
    17. "Simmer pus and grow flesh" method promotes chronic wound healing in rats viabFGF-Wnt β-catenin signaling pathway Cellular and Molecular Biology · 2024 · 1 citations
    18. Soy protein/β-chitin sponge-like scaffolds laden with human mesenchymal stromal cells from hair follicle or adipose tissue promote diabetic chronic wound healing Biomaterials advances · 2023 · 1 citations
    19. Application and progress of induced pluripotent stem in chronic wound healing: a narrative review BMC Plastic and Reconstructive Surgery · 2026
    20. Advances in Chronic Wound Management: The Role of Antibiofilm-Based Wound Dressings and Theranostic Innovations International Journal of Drug Delivery Technology · 2026
    21. Alkaline pH-responsive polymeric swelling in chronic wound identification and on-demand healing Applied Materials Today · 2026
    22. Platelet - Rich Plasma (PRP) and Platelet - Rich Fibrin (PRF) Clot Dressing in Chronic Wound Management: Two Case Reports International Journal of Science and Research (IJSR) · 2023
    23. 577 Successful allogeneic epidermal grafting of chronic recessive dystrophic epidermolysis bullosa wounds from hematopoietic cell donors in the outpatient setting Journal of Investigative Dermatology · 2019
    24. A Smart Bandage Equipped with Miniaturized Needle Arrays and Wirelessly-Controlled Drug Delivery System for the Treatment of Chronic Wounds Lincoln (University of Nebraska) · 2019
    25. Rothmund‐Thomson syndrome type 2 – a rare cause of chronic wounds Journal der Deutschen Dermatologischen Gesellschaft · 2019
    26. A stretchable wireless wearable bioelectronic system for multiplexed monitoring and combination treatment of infected chronic wounds Science Advances · 2023 · 319 citations
    27. Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects International Journal of Molecular Sciences · 2021 · 70 citations
    28. Regeneration of Chronic Wounds with Allogeneic Platelet Gel versus Hydrogel Treatment: a Prospective Study Acta Clinica Croatica · 2018 · 25 citations
    29. Long Ya Cao (Agrimonia pilosa Ledeb.) extract and its bioactive constituent (agrimonolide) attenuate chronic inflammation and accelerate wound healing in rats through regulating oxidative-inflammatory markers and stimulating collagen production Pharmacological Research - Modern Chinese Medicine · 2026
    30. Nanotechnology Approaches in Chronic Wound Healing Advances in Wound Care · 2020 · 110 citations