November 2024 in “Journal of Investigative Dermatology” This study identified PTEN as a key regulator in non-healing venous leg ulcers, suppressing immune responses and lymphangiogenesis, suggesting its potential as a therapeutic target for promoting VLU healing.
September 2026 in “Wound Repair and Regeneration” This systematic review suggests that stem cell-based therapies may offer potential benefits for healing pure venous ulcers, but findings are preliminary due to small sample sizes and varied interventions.
April 2026 in “Frontiers in Bioengineering and Biotechnology” This study found that a cellulose membrane significantly shortened the healing time and reduced the ulcer area in patients with chronic venous leg ulcers compared to a standard antimicrobial dressing.
4 citations
,
January 2016 in “JAMA Dermatology” This article discusses potential benefits of increasing active range of motion in the care of venous leg ulcers but reports no new clinical results.
2 citations
,
August 2021 in “Journal of The American Academy of Dermatology” In this study, researchers reviewed the literature on the preventive and therapeutic roles of exercise in various skin diseases and assessed whether there are sufficient data to recommend exercise for each condition.