Nanotechnology Approaches in Chronic Wound Healing

The document reviewed various nanotechnology approaches for chronic wound healing, particularly in diabetic models. It highlighted the potential of nanoparticles, nanofibers, and nanocomposites in enhancing wound healing through antimicrobial activity, drug delivery, and tissue regeneration. Key findings included the use of silver, gold, copper, and zinc oxide nanoparticles for their antibacterial properties and promotion of angiogenesis and collagen deposition. Nanofibers and liposomes were noted for their ability to mimic the extracellular matrix and provide sustained release of therapeutic agents. Despite promising preclinical results, the review emphasized the need for further research and clinical trials to confirm the efficacy and safety of these nanotechnology-based treatments in humans.