The Effect of Nanoparticle-Incorporated Natural-Based Biomaterials on Cells and Activated Pathways: A Systematic Review

This review highlights cellulose-based materials' potential in skin disease treatments, emphasizing their smart, responsive design for various conditions, with insights into their roles in wound healing, infection prevention, and wearable monitoring.

This article reviews the potential of bionanomaterials, derived from natural biomolecules, for wound healing and reports no new clinical results; it emphasizes the need for further research in this area.

This research systematically reviewed studies on natural-based hydrogel, hydrocolloid, and hydrofiber dressings for diabetic wound healing, finding they exhibit antimicrobial, anti-inflammatory, and other beneficial effects, but noted the need for standardized models and regulatory compliance to enhance clinical translation.

In this review, cellulose-based nanofibers are highlighted for their potential in wound care, given their biodegradability, biocompatibility, and ability to enhance antimicrobial properties and drug delivery in wound dressings through modern fabrication techniques like electrospinning.

This review highlights that incorporating nanomaterials into scaffolds can significantly enhance angiogenesis in tissue regeneration by simulating extracellular matrix structures and effectively delivering angiogenesis-related factors, offering promising designs for vascularization and therapeutic applications.