Injectable Biomaterials for Dental Tissue Regeneration

    Håvard Jostein Haugen, Poulami Basu, Mousumi Sukul, João F. Mano, Janne E. Reseland
    Studysummary This narrative review discusses the role of injectable biomaterials in dental tissue regeneration, highlighting their suitability for treating small, hard-to-access oral defects compared to pre-formed scaffolds, and explores the potential use of nanofibers in dental applications.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The narrative review discussed the role of injectable biomaterials in dental tissue regeneration, emphasizing their advantages over pre-formed scaffolds, particularly in challenging areas like the maxilla-oral region. Injectable biomaterials, including hydrogels, micro-nanoparticles, and natural/synthetic scaffolds, were effective in regenerating craniofacial and dental tissues by restoring function and biological purpose. The review highlighted the potential of hydrogels to release growth factors and anti-inflammatory agents, promoting tissue regeneration and serving as alternatives to traditional bone grafts. Various biomaterials, such as fibrin, chitosan, alginate, and Emdogain, demonstrated promise in enhancing dental tissue regeneration, though further research and clinical trials were needed. The document concluded that regenerative endodontics, involving cell therapy and growth factors, was expected to be a promising approach in regenerative dental medicine.
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