Wnt Signaling Induces Epithelial Differentiation During Cutaneous Wound Healing

    July 2015 in “ Organogenesis ”
    Khosrow Siamak Houschyar, Arash Momeni, M.N. Pyles … Frank Siemers
    Studysummary This review summarizes recent findings on how Wnt signaling proteins play crucial roles in the cutaneous wound healing process but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures Plastic and Reconstructive Surgery · 2013
    2. Augmenting Endogenous Wnt Signaling Improves Skin Wound Healing PLoS ONE · 2013
    3. Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding Nature Medicine · 2013
    4. Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    5. Wnt Signaling in Skin Development, Homeostasis, and Disease Cold Spring Harbor Perspectives in Biology · 2012
    6. Cutaneous Wound Healing: Recruiting Developmental Pathways for Regeneration Cellular and Molecular Life Sciences · 2012
    7. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012
    8. Wound Repair at a Glance Journal of Cell Science · 2009
    9. Fetal Skin Wound Healing Advances in Clinical Chemistry · 2009
    10. Wnt Signaling in Skin Organogenesis Organogenesis · 2008
    11. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    12. Scratching the Surface of Skin Development Nature · 2007
    13. Wnt Signaling Induces Epithelial Differentiation During Cutaneous Wound Healing BMC Cell Biology · 2006
    14. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005

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