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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Peppermint

      herb and oil thought to stimulate skin and hair

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community One year on finasteride has reversed some aging

      in Chat  198 upvotes 1 week ago
      Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

      community 4.5 months on 1mg fin/6%min/2.5mg biotin hybrid progress

      in Is this regrowth?  58 upvotes 6 months ago
      A 25-year-old male experienced hair regrowth after 4.5 months using a chewable treatment with 1mg finasteride, 6% minoxidil, and 2.5mg biotin, despite initial shedding and acne from accutane. Opinions on progress vary, with some noticing thicker hair and others seeing no difference or thinning.

      community Realistically, how much PP405 will cost?

      in Treatment  30 upvotes 9 months ago
      PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  35 upvotes 2 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.