An Insight Into Biodegradable Polymers and Their Biomedical Applications for Wound Healing
July 2024
in “
Current Pharmaceutical Design
”
biodegradable polymers natural polymers synthetic polymers nanoparticle-loaded hydrogels nanofibrous scaffolds hyaluronic acid collagen polylactic acid cell proliferation angiogenesis hair growth wound management chronic wounds polymeric scaffolds hydrogels scaffolds cell growth blood vessel formation wound care
TLDR Biodegradable polymers help wounds heal faster.
The document reviews the use of biodegradable polymers in wound healing, focusing on both natural (e.g., hyaluronic acid, collagen, chitosan) and synthetic (e.g., polylactic acid, polyglycolic acid) materials. It highlights advanced materials like nanoparticle-loaded hydrogels and nanofibrous scaffolds that enhance cell proliferation, angiogenesis, hair growth, and wound management. The review emphasizes the effectiveness of chitosan-based materials, especially when combined with other substances like silver nanoparticles and gelatin, in promoting wound healing through antibacterial properties and enhanced drug delivery. Numerous in vitro and in vivo studies show that these materials accelerate wound healing, reduce inflammation, and improve tissue regeneration, making them valuable for advanced wound dressings.
