Modulation of Macrophage Functions by ECM-Inspired Wound Dressings – A Promising Therapeutic Approach for Chronic Wounds

The document reviewed the potential of ECM-inspired wound dressings to modulate macrophage functions as a therapeutic approach for chronic wounds. It highlighted the importance of macrophages in wound healing and discussed how ECM-inspired materials could be used to control macrophage activity. These materials mimic the extracellular matrix's ability to bind and deliver signaling molecules, directly influencing macrophage behavior. The review provided examples of recent advancements in this field and suggested directions for future research to improve chronic wound treatment.