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    Glossary Chronic Alopecia Areata

    long-term autoimmune condition causing persistent hair loss

    Chronic Alopecia Areata (Chronic AA) is a long-term autoimmune condition where the immune system mistakenly attacks hair follicles, leading to persistent and often unpredictable hair loss on the scalp and other parts of the body. Unlike acute cases, which may resolve within a year, chronic AA can last for several years or even be lifelong, requiring ongoing management and treatment.

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    Research 10 of 1000+

    1. Role of Cytotoxic T Cells in Chronic Alopecia Areata Journal of Investigative Dermatology · 2000 · 127 citations
    2. Role of platelet-rich plasma in chronic alopecia areata: Our centre experience Indian Journal of Plastic Surgery · 2015 · 61 citations
    3. Utility of azathioprine, methotrexate and cyclosporine as steroid‐sparing agents in chronic alopecia areata: a retrospective study of continuation rates in 138 patients 2020 · 12 citations
    4. Predominant expression of interleukin (IL)‐17 in chronic alopecia areata compared to IFN‐γ in pathogenic Th17 cells, tissue‐resident memory T cells and natural killer cells JEADV Clinical Practice · 2023 · 3 citations
    5. 068 Pathogenic Th17 cells, CD8+CD69+CD49a- tissue-resident memory T cells and common γ chain receptor + natural killer cells express more IL-17, compared to IFN-γ, under the foxp3+ memory regulatory T cells-depleted microenvironment in patients with chronic alopecia areata Journal of Investigative Dermatology · 2023
    6. 083 More Expression of IL-17 than IFN-γ from CD49a-negative Tissue-Resident Memory T (Trm) cells at the Hair Bulge and Hair Bulb Region in the Scalp of Chronic Alopecia Areata Patients according to the Foxp3+mTregs depletion Journal of Investigative Dermatology · 2019
    7. 44179 Characterization of subclinical atherosclerosis in chronic severe alopecia areata. Journal of the American Academy of Dermatology · 2023
    8. 470 Exploring the possible involvement of skin-resident memory T cells in refractory chronic alopecia areata Journal of Investigative Dermatology · 2025
    9. Limited Effectiveness of Platelet-Rich-Plasma Treatment on Chronic Severe Alopecia Areata Hair therapy & transplantation · 2014 · 15 citations
    10. PRP therapy in chronic diffuse alopecia areata – A case report IP Indian journal of clinical and experimental dermatology · 2021
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    Community 8 of 30

    1. 25M Exploring Causes of Hair Loss: TE, Alopecia, or AGA? Community · 26 Aug 2025
    2. From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA. Reddit · 10 Apr 2026
    3. Could Finasteride theoretically induce chronic telogen effluvium? Reddit · 9 Feb 2025
    4. Is 2years+ telogen effluvium possible? Reddit · 5 Jul 2024
    5. Thoughts on this Article: Post-Finasteride and Neurological Effects Reddit · 16 Mar 2024
    6. Sharing what worked for me (PCOS related hair loss) Reddit · 16 Jan 2024
    7. 26F Thinner hair due to vitamin deficiencies? Reddit · 23 Dec 2023
    8. 1 and a half years on fin - hair is way worse. Reddit · 24 Apr 2023
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    1. Neem Oil Oil from the neem tree, used in traditional remedies