56 citations,
March 2016 in “International Wound Journal” Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
28 citations,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
15 citations,
August 2022 in “Journal of endocrinological investigation” Vitamin D and calcium are important for quick and effective skin wound healing.
9 citations,
March 2023 in “Biomimetics” New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.
4 citations,
January 2016 in “Elsevier eBooks” Animal experiments help understand and test treatments for healing wounds and reducing scars.
2 citations,
May 2022 in “JAAD case reports” Using powdered umbilical remnant allograft can effectively treat chronic scalp wounds resistant to traditional treatments.
2 citations,
November 2023 in “Curēus” Platelet-rich plasma (PRP) speeds up skin wound healing and has potential in medical and cosmetic uses.
2 citations,
September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
April 2018 in “Journal of Investigative Dermatology” Basonuclin 1 (BNC1) helps skin cells multiply and move, which is crucial for wound healing.
February 2022 in “Journal of Investigative Dermatology” Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.
August 2021 in “International Journal of Dermatology and Venereology” Platelet-Rich Fibrin (PRF) can speed up healing in chronic wounds, improve hair density, and act as a natural filler for skin rejuvenation, but its use in hair loss treatment needs more evaluation.
20 citations,
August 2022 in “Frontiers in Immunology” Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
6 citations,
June 2017 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Transplanting hair follicles into chronic ulcers helps them heal better.
3 citations,
March 2023 in “Life” Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
2 citations,
December 2023 in “International journal of molecular sciences” Wound healing is greatly affected by the types of bacteria present, which can either help or hinder the process.
May 2023 in “Stem Cells International” Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
5 citations,
February 2024 in “Frontiers in bioengineering and biotechnology” Electrospun scaffolds can improve healing in diabetic wounds.
20 citations,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
238 citations,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
65 citations,
May 2017 in “Advances in wound care” Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
33 citations,
September 2012 in “Wound Repair and Regeneration” Applying calreticulin can speed up wound healing in diabetics.
1 citations,
March 2023 in “Colloids and surfaces. B, Biointerfaces” A new wound dressing with p-Coumaric acid helps heal diabetic wounds faster by reducing inflammation and promoting skin repair.
November 2023 in “International Journal of Biological Macromolecules” The gelatin-based hydrogel helps heal acute and diabetic wounds faster by improving healing conditions.
24 citations,
September 2020 in “Pharmaceutics” Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.
January 2014 in “Indian dermatology online journal” Different treatments help heal leg ulcers depending on their type, with new therapies showing promise for chronic wounds.
113 citations,
June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
40 citations,
December 2015 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
3 citations,
June 2023 in “MedComm” Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.
Enterococcus faecalis delays wound healing by disrupting cell functions and creating an anti-inflammatory environment.