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    Did you mean 3D cell spheroids?
    Glossary 3D cell spheroids

    clusters of cells growing in three-dimensional structures

    3D cell spheroids are clusters of cells that grow in a three-dimensional structure, mimicking the natural environment of tissues more accurately than traditional two-dimensional cell cultures. These spheroids are used in research to study cell behavior, drug responses, and disease mechanisms, providing a more realistic model for biological processes and potential treatments.

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    1. Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroid of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration ACS Applied Materials & Interfaces · 2016 · 62 citations
    2. 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects iScience · 2024 · 13 citations
    3. 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA) Cells · 2022 · 2 citations
    4. Establishment of 3D Spheroid Human Dermal Papilla Cells as an Effective Model for Hair Growth Screening Compounds Compared with the 2D System: An Example of Minoxidil and 3,4,5-Tri-O-caffeoylquinic acid (TCQA) Research Square (Research Square) · 2021
    5. In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers Scientific Reports · 2017 · 14 citations
    6. 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-caffeoylquinic acid (TCQA) Institutional Repositories DataBase (IRDB) · 2022
    7. Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture Tissue engineering. Part A · 2014 · 46 citations
    8. Comparative analysis of 3D and 2D cell-culturing methods in hair follicle spheroid morphogenesis and drug responsiveness Biomaterials Advances · 2025 · 1 citations
    9. High-Throughput 3D Spheroid Production with Photocurable Polyurethane Microwell Arrays via LCD 3D Printing 2026
    10. Self-Organizing 3D Dermal Papilla Cell Spheroids Yield Therapeutic Extracellular Vesicles that Target Hypertrophic Scar Regression via the miR-26a-5p/CCNE2 Axis Burns & Trauma · 2025
    11. 569 Application of 3D scaffold free dermal spheroids to investigate retinol and retinol alternatives mechanism of action on extracellular matrix Journal of Investigative Dermatology · 2024
    12. Monte Carlo simulation‐guided design for size‐tuned tumor spheroid formation in 3D printed microwells Biotechnology Progress · 2024 · 2 citations
    13. Methods for the isolation and 3D culture of dermal papilla cells from human hair follicles Experimental Dermatology · 2017 · 55 citations
    14. Wnt activator CHIR99021-stimulated human dermal papilla spheroids contribute to hair follicle formation and production of reconstituted follicle-enriched human skin Biochemical and Biophysical Research Communications · 2019 · 40 citations
    15. TGF-β2 and collagen play pivotal roles in the spheroid formation and anti-aging of human dermal papilla cells Aging · 2021 · 11 citations
    16. Biological and mechanical influence of three-dimensional microenvironment formed in microwell on multicellular spheroids composed of heterogeneous hair follicle stem cells Scientific reports · 2023 · 1 citations
    17. 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration Acta Biomaterialia · 2022 · 15 citations
    18. 600 Differential Molecular Signature of Dermal Papilla Cells (DPCs) from Balding and Non balding Scalp in 2D, 3D culture and Co-culture with Adipose-derived stem cells (ASCs) Journal of Investigative Dermatology · 2019
    19. 1333 Spheroids cell cultures as a promising study model for hair follice regeneration Journal of Investigative Dermatology · 2018
    20. 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance Journal of Investigative Dermatology · 2016
    21. Flavonoid Silibinin Increases Hair-Inductive Property Via Akt and Wnt/��-Catenin Signaling Activation in 3-Dimensional-Spheroid Cultured Human Dermal Papilla Cells Journal of Microbiology and Biotechnology · 2019 · 29 citations
    22. Using bioprinting and spheroid culture to create a skin model with sweat glands and hair follicles Burns & Trauma · 2021 · 65 citations
    23. High-throughput screening of 3D co-culture hair follicle mimetic tissue with enhanced ECM for the screening of hair growth promoting compounds Biomaterials Research · 2024
    24. 1324 Impairment of hair-inducing capacity of 3D-cultured human dermal papilla cells by the ablation of STAT5 Journal of Investigative Dermatology · 2018
    25. Titrated extract of<i>Centella asiatica</i>increases hair inductive property through inhibition of STAT signaling pathway in three-dimensional spheroid cultured human dermal papilla cells Bioscience, Biotechnology, and Biochemistry · 2017 · 13 citations
    26. Literature review of 3D-bio printed hair follicles and the proposal for a permanent hair system on the scalp UVic’s Research and Learning Repository (University of Victoria) · 2024
    27. Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway PeerJ · 2022 · 4 citations
    28. HIF-1α Stimulators Function Equally to Leading Hair Loss Agents in Enhancing Dermal Papilla Growth Skin Pharmacology and Physiology · 2020 · 6 citations
    29. Dermal papilla regulation of hair growth and pigmentation Advances in stem cells and their niches · 2019 · 3 citations
    30. Culture Strategy Determines the Differentiation Status of Sweat Gland Cells Cells · 2025