Hair Growth Promoting Effects of 15-Hydroxyprostaglandin Dehydrogenase Inhibitor in Human Follicle Dermal Papilla Cells

    July 2024 in “ International Journal of Molecular Sciences ”
    NULL AUTHOR_ID, Hak Joong Kim, NULL AUTHOR_ID … Dong Wook Shin
    Studysummary This study explored the effects of DPP, a 15-PGDH inhibitor, on human follicle dermal papilla cells damaged by dihydrotestosterone and observed that DPP enhanced wound healing, reduced reactive oxygen species, and increased hair growth in ex vivo human hair follicle cultures.
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    Research cited in this study 37

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    2. The Efficacy of Topical Prostaglandin Analogs for Hair Loss: A Systematic Review and Meta-Analysis Frontiers in Medicine · 2023
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    Related research 6

    1. TGFβ Family Mimetic Peptide Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice Biomedical dermatology · 2018
    2. Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth PLOS ONE · 2016
    3. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    4. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    5. Melanocyte Subpopulation Turnover During the Human Hair Cycle: An Immunohistochemical Study Pigment cell research · 2000
    6. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996