61 citations,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
16 citations,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
December 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Scientists found a new method using 3D cell cultures to grow human hair which may improve hair restoration treatments.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
1 citations,
March 2024 in “Nanomaterials” Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
35 citations,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
19 citations,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
16 citations,
July 2020 in “Advanced functional materials” 3D cell-derived matrices improve tissue regeneration and disease modeling.
62 citations,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
46 citations,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
2 citations,
June 2022 in “Cells”
26 citations,
March 2013 in “Journal of Biomedical Materials Research Part A” Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.
1 citations,
January 2023 in “Burns and trauma” Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
2 citations,
April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
2 citations,
May 2021 in “International journal of molecular sciences” Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
7 citations,
June 2021 in “Cell Proliferation” Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
83 citations,
May 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
6 citations,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
38 citations,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
2 citations,
February 2024 in “Nature cell biology” Mechanical forces are crucial for shaping cells and forming tissues during development.
10 citations,
May 2019 in “BMC Complementary and Alternative Medicine” The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
28 citations,
September 2020 in “Pharmaceutics” 3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.
57 citations,
May 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
31 citations,
August 2019 in “Regenerative Medicine” Human placenta hydrogel helps restore cells needed for hair growth.
13 citations,
September 2020 in “Experimental Cell Research” PCAT1 helps hair growth by controlling miR-329/Wnt10b.
65 citations,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.