Bacillus/Trapa Japonica Fruit Extract Ferment Filtrate Enhances Human Hair Follicle Dermal Papilla Cell Proliferation via the Akt/ERK/GSK-3β Signaling Pathway
May 2019
in “
BMC Complementary and Alternative Medicine
”
TLDR The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
In the 2019 study, Bacillus/Trapa japonica fruit extract ferment filtrate (TJFs) was found to stimulate human hair follicle dermal papilla (HDP) cell proliferation and migration via the Akt/ERK/GSK-3β signaling pathway. The treatment with TJFs led to increased expression of hair growth factors, progression of the cell cycle, reduced apoptosis, enhanced angiogenesis, and decreased activity of type I 5α-reductase, which is associated with hair loss. The study's assays and models confirmed these effects, suggesting TJFs could be a promising treatment for alopecia. The number of participants or cells used in the study was not specified in the provided text.
