Biomimetic Scaffolds: A Novel Approach to Three-Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering
March 2024
in “
Nanomaterials
”
TLDR Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
The article reviews advancements in biomimetic scaffolds for three-dimensional (3D) cell culture techniques, emphasizing their superiority over traditional two-dimensional (2D) cultures in mimicking natural tissue environments. These scaffolds, made from materials like hydrogels and decellularized extracellular matrix (dECM), support cell adhesion, proliferation, and differentiation, crucial for tissue regeneration. The review highlights the potential of these scaffolds in regenerating various tissues, including skin, musculoskeletal, endocrine, and genitourinary systems, and underscores the need for further research to ensure their safety and efficacy in clinical applications. Advanced 3D bioprinting techniques, including 4D bioprinting, are also discussed for their role in creating dynamic, responsive biomaterials for tissue engineering and regenerative medicine.
