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Glossary2D cell culture

cells grown on flat surfaces for research purposes

2D cell culture, also known as two-dimensional cell culture, is a laboratory technique where cells are grown on a flat, typically plastic, surface such as a petri dish. This method allows researchers to study cell behavior, drug responses, and biological processes in a controlled environment, but it may not fully replicate the complex interactions found in a living organism.

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research Peer Review of Establishment of an Immortalized Mouse Dermal Papilla Cell Strain with Optimized Culture Strategy

January 2018

Scientists improved how to grow mouse skin cells in the lab and created a long-lasting cell line, but didn't fully explain its advantages or compare it to normal cells.

research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)

2 citations, June 2022 in “Cells”

3D cell cultures are better for testing hair growth treatments than 2D cultures.

research Biomimetic Scaffolds: A Novel Approach to Three-Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

1 citations, March 2024 in “Nanomaterials”

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

Establishment of 3D Spheroid Human Dermal Papilla Cells as an Effective Model for Hair Growth Screening Compounds Compared with the 2D System: An Example of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid

research Establishment of 3D Spheroid Human Dermal Papilla Cells as an Effective Model for Hair Growth Screening Compounds Compared with the 2D System: An Example of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid

November 2021 in “Research Square (Research Square)”

3D spheroid cultures of human hair follicle cells are better for hair growth research than 2D cultures, and they provide new insights into how hair growth treatments like minoxidil and TCQA work.

Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration

research Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration

62 citations, February 2016 in “ACS Applied Materials & Interfaces”

Technique creates 3D cell spheroids for hair-follicle regeneration.

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community Scientists have found that a naturally occurring sugar in humans and animals could be used as a topical treatment for male pattern baldness | In the study, mice received 2dDR-SA gel for 21 days, resulting in greater number of blood vessels and an increase in hair follicle length and denseness

in Research/Science 634 upvotes 3 months ago

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

community 11mth daily 0.5mg oral finasteride

in Finasteride/Dutasteride 794 upvotes 6 days ago

The user experienced significant hair regrowth with 0.5mg oral finasteride daily, despite a minoxidil allergy, and reported no side effects. They also used a keto shampoo and were satisfied with the results.

community Are topicals with caffeine useful to promote hairgrowth?

in Research/Science 3 upvotes 6 months ago

The user is asking if caffeine topicals are effective for hair growth, noting they already use Minoxidil and finasteride. They are unsure if caffeine topicals are beneficial or a waste of money.

community Hair Tattoo as a substitue to hair transplant

in Transplants 517 upvotes 1 year ago

A hair tattoo substitute for a hair transplant, which many people felt was not a good idea. Several treatments were suggested as alternatives, such as Scalp Micro Pigmentation (SMP) and wigs.

community 24M , been a month on minoxidil Finastride nizoral any difference ?

in Treatment 153 upvotes 2 years ago

A user who has been taking minoxidil, finasteride and nizoral for one month, asking if there is any difference in their hair loss; the responses suggest that some improvement may have been seen but it can be hard to tell with just one month of treatment.