Interventions for Hirsutism Excluding Laser and Photoepilation Therapy Alone: Abridged Cochrane Systematic Review Including GRADE Assessments
February 2016
in “
British journal of dermatology/British journal of dermatology, Supplement
”
hirsutism oral contraceptives OCPs ethinyl oestradiol cyproterone acetate desogestrel flutamide spironolactone finasteride gonadotropin-releasing analogues metformin Ferriman–Gallwey scores antiandrogens 5α-reductase inhibitors birth control pills ethinyl estradiol Propecia GnRH analogues 5-alpha-reductase inhibitors
Studysummary This review found moderate to very low-quality evidence that spironolactone, flutamide, and cyproterone acetate combined with oral contraceptives may reduce hirsutism more effectively than placebo or metformin, though results vary among other treatments.
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