Effect of Leuprolide and Dexamethasone on Hair Growth and Hormone Levels in Hirsute Women: The Relative Importance of the Ovary and the Adrenal in the Pathogenesis of Hirsutism

    April 1990 in “ The Journal of Clinical Endocrinology & Metabolism ”
    Roger S. Rittmaster, David L. Thompson
    Studysummary This study found that ovarian suppression significantly reduced serum testosterone and androstenedione in women with polycystic ovarian syndrome and idiopathic hirsutism, with hair growth rates decreasing more in polycystic ovarian syndrome.
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    Research cited in this study 4

    1. Differential Suppression of Testosterone and Estradiol in Hirsute Women With the Superactive Gonadotropin-Releasing Hormone Agonist Leuprolide The Journal of Clinical Endocrinology & Metabolism · 1988
    2. Clinical and Hormonal Effects of Chronic Gonadotropin-Releasing Hormone Agonist Treatment in Polycystic Ovarian Disease The Journal of Clinical Endocrinology & Metabolism · 1987
    3. Clinical Usefulness of Plasma Androstanediol Glucuronide Measurements in Women with Idiopathic Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1987
    4. Treatment of Hirsutism with a Gonadotropin-Releasing Hormone Agonist (Nafarelin) ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1986