TLDR The photographic method accurately measures hair growth and both treatments effectively reduced hair growth in hirsute women.
In 1991, a study demonstrated that a photographic method for measuring linear hair growth was reliable and reproducible for use in a clinical setting. The study involved 41 hirsute women who were treated with anti-androgens. Group A, consisting of 21 women, received spironolactone and Ovysmen for 6 months, while Group B, with 20 women, was treated with cyproterone acetate and ethinyloestradiol for the same duration. Results showed a significant reduction in hair growth, with Group A experiencing a 29% decrease and Group B a 37% decrease. Additionally, the Ferriman Gallwey score, which assesses hair growth severity, dropped by 39% in Group A and 43% in Group B. No significant difference in treatment response was found between the two groups. This photographic method was deemed useful for managing hirsutism in women.
78 citations,
May 1989 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
9 citations,
December 1987 in “European journal of endocrinology” The treatment significantly reduced hair growth and male hormone levels in hirsute women.
50 citations,
August 1985 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
32 citations,
August 1985 in “Clinical endocrinology” Spironolactone may help reduce hair growth and testosterone levels in some women with hirsutism.
18 citations,
August 1985 in “European journal of endocrinology” Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.
142 citations,
February 1985 in “Fertility and sterility” Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.
183 citations,
March 1982 in “JAMA” Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.
66 citations,
October 1977 in “British journal of dermatology/British journal of dermatology, Supplement” Cyproterone acetate reduces hair growth and oil production.
39 citations,
January 1980 in “Dermatology” Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.
8 citations,
November 1978 in “British journal of dermatology/British journal of dermatology, Supplement” Cyproterone acetate can effectively treat idiopathic hirsutism, but ethinyl oestradiol and lynoestrenol may not always reduce hair growth.
