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GlossaryDesogestrel

synthetic hormone used in birth control to prevent ovulation

Desogestrel is a synthetic hormone used in some birth control pills. It mimics the natural hormone progesterone, helping to prevent ovulation and making it harder for sperm to reach the uterus. This hormone is often chosen for its lower risk of side effects compared to other synthetic progestins.

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research The Treatment of Hirsutism with a Combination of Desogestrel and Ethinyl Estradiol

64 citations, January 1985 in “Clinical endocrinology”

A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.

research Effects of a Low-Dose Desogestrel-Ethinylestradiol Combination on Hirsutism, Androgens, and Sex Hormone Binding Globulin in Women with Polycystic Ovary Syndrome

53 citations, January 1985 in “Acta obstetricia et gynecologica Scandinavica”

Low-dose oral contraceptives reduced hair growth and testosterone levels in women with polycystic ovary syndrome.

research Effectiveness of Low-Dose Ethinylestradiol/Cyproterone Acetate and Ethinylestradiol/Desogestrel with and without Metformin on Hirsutism in Polycystic Ovary Syndrome: A Randomized, Double-Blind, Triple-Dummy Study

5 citations, July 2020 in “PubMed”

Both oral contraceptives reduced hirsutism in PCOS patients, but adding metformin showed no extra benefit.

research Suppression of Spermatogenesis with Desogestrel and Testosterone Pellets Is Not Enhanced by Addition of Finasteride

31 citations, January 2001 in “PubMed”

research Venous and Pulmonary Thromboembolism and Combined Hormonal Contraceptives: Systematic Review and Meta-Analysis

63 citations, January 2012 in “The European Journal of Contraception & Reproductive Health Care”

Some birth control pills have a higher risk of blood clots than others.

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community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 56 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.