16 citations,
March 2008 in “International journal of pharmaceutics” Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
61 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.
2 citations,
April 2021 in “International Journal of Pharmaceutics” Serum formulations were better at delivering molecules to the hair bulb than nanoparticles.
January 2015 in “Elsevier eBooks” Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.
182 citations,
December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
128 citations,
July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
94 citations,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
82 citations,
May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
69 citations,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
62 citations,
October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
55 citations,
January 2016 in “Annals of Dermatology” Microneedle stimulation can increase hair growth in mice.
55 citations,
July 1999 in “Clinics in Sports Medicine” Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
51 citations,
May 2010 in “Journal of Drug Targeting” Transcutol-containing vesicles improve minoxidil's skin penetration and hair growth promotion.
39 citations,
November 2016 in “Pharmaceutics” The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
39 citations,
February 2014 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
38 citations,
September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
28 citations,
August 2000 in “Current Opinion in Chemical Biology” Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
23 citations,
September 2018 in “Dermatologic Therapy” Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.
16 citations,
November 2020 in “International journal of pharmaceutics” Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
16 citations,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
14 citations,
September 2019 in “Saudi pharmaceutical journal” Microparticles help caffeic acid stay longer in hair follicles for better treatment of folliculitis.
13 citations,
February 2018 in “Bio-medical Materials and Engineering” Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
12 citations,
July 2020 in “International Journal of Pharmaceutics” Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
11 citations,
June 2020 in “Journal of cosmetic dermatology” Home-use microneedle devices might safely boost 5% minoxidil's effectiveness for hair growth.
11 citations,
April 2009 in “Pharmacotherapy” Minoxidil can cause deadly skin reaction; monitor patients closely.
11 citations,
March 2007 in “Journal of Hypertension” Minoxidil effectively lowers blood pressure in resistant cases, but needs beta-blocker and diuretic support.
10 citations,
June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
9 citations,
October 2013 in “Drug Delivery” Ethosomal carriers effectively deliver hair loss drug into skin.
6 citations,
December 2015 in “International journal of nanomedicine” Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.
5 citations,
April 2019 in “Plastic and reconstructive surgery. Global open” Fractional lasers could help hair regrowth in androgenic alopecia, but more research is needed to confirm their effectiveness and safety.