Acquired Localized Hypertrichosis Induced by Rivastigmine

January 2016 in “ Case reports in dermatological medicine ”

Adrián Imbernón‐Moya, Sebastián Podlipnik, Fernando Burgos, Elena Vargas-Laguna, Antonio Aguilar-Martínez, Eva Fernández-Cogolludo, Miguel Ángel Gallego-Valdés

localized hypertrichosis rivastigmine acetylcholinesterase inhibitors butyrylcholinesterase inhibitors norgalanthamine dermal papilla

TLDR An 80-year-old man grew extra hair on his forearms after starting Alzheimer's medication rivastigmine.

An 80-year-old male with Alzheimer's disease developed localized hypertrichosis on his forearms after starting oral rivastigmine. Diagnostic tests and a skin biopsy were normal, confirming rivastigmine as the cause. Despite this side effect, rivastigmine treatment continued due to its importance for Alzheimer's management, and the hypertrichosis did not spread further over a year. This case revealed a previously unreported side effect of rivastigmine.

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