12 citations
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January 2010 in “European Journal of Dermatology” In this study, an ethanol extract of Crinum asiaticum was observed to significantly increase hair-fiber lengths and promote hair growth in rat vibrissa follicles and C57BL/6 mice.
5 citations
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December 2018 in “Biological & Pharmaceutical Bulletin” In this study, norgalanthamine was found to stimulate hair growth in cultured rat dermal papilla cells by activating the ERK 1/2, PI3K/AKT, and Wnt/β-catenin signaling pathways.
3 citations
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January 2016 in “Case reports in dermatological medicine” This report discusses a case of localized hypertrichosis that developed after an elderly male with Alzheimer's disease started oral rivastigmine therapy, suggesting a potential link between the drug and hair growth.
This study suggests that Crinum asiaticum var. japonicum extract and its component norgalanthamine may promote hair growth by inhibiting 5α-reductase activity and the TGF-β1-induced pathway.