TLDR Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
The study investigated the interaction of nanodiamonds (NDs) with skin tissue, focusing on their penetration and localization using various optical techniques. Researchers found that NDs could penetrate the skin, primarily through hair follicles, and localize within specific tissue regions. The size and surface properties of NDs influenced their distribution, with 100 nm particles being suitable for multimodal imaging. The findings suggested potential applications for NDs in drug delivery, medical imaging, and skin protection, although further research on nanosafety and biocompatibility was recommended.
Cited in this study
6 / 6 results
59 citations
,
July 2015 in “Journal of innovative optical health sciences/Journal of innovation in optical health science” Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
83 citations
,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
263 citations
,
February 2011 in “Journal of Controlled Release” Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.
264 citations
,
January 2008 in “Journal of biomedical optics” Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.
788 citations
,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
323 citations
,
June 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” Only 40 nm nanoparticles can enter skin cells effectively for potential vaccine delivery.
