Optical Studies of Nanodiamond-Tissue Interaction: Skin Penetration and Localization

    November 2019 in “ Materials
    E. Perevedentseva, Nsrein Ali, Artashes Karmenyan, Ilya Skovorodkin, Renata Prunskaitė-Hyyryläinen, Seppo Vainio, Chia‐Liang Cheng, Matti Kinnunen
    TLDR Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
    The study investigated the interaction of nanodiamonds (NDs) with skin tissue, focusing on their penetration and localization using various optical techniques. Researchers found that NDs could penetrate the skin, primarily through hair follicles, and localize within specific tissue regions. The size and surface properties of NDs influenced their distribution, with 100 nm particles being suitable for multimodal imaging. The findings suggested potential applications for NDs in drug delivery, medical imaging, and skin protection, although further research on nanosafety and biocompatibility was recommended.
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