Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this review, Ziziphus lotus was reported to have multiple traditional uses and demonstrated various pharmacological properties in lab and animal studies, with over 181 identified bioactive compounds; however, clinical trials are needed to confirm its efficacy as a medicinal agent.

This study found that the humanin analogue HNG significantly promoted hair growth in vitro and in vivo by prolonging the anagen phase and inhibiting hair follicle cell apoptosis in mice.

This review evaluates traditional uses, phytochemical profiles, and pharmacological activities of Mediterranean Erica species, revealing the wide range of bioactive compounds and highlighting their antioxidant, anti-inflammatory, and antimicrobial activities. Further studies are suggested to fully understand their medicinal potential.

This review identifies agri-food by-products as promising sources of antioxidant compounds for cosmeceutical applications, examining their potential for skin, oral, and hair care, while noting the need for further research on safety and clinical efficacy.

This review highlights how cyclodextrin-polysaccharide hybrids can advance drug delivery and environmental cleanup by improving the solubility and stability of hydrophobic molecules, serving as promising platforms for biomedical applications and efficient sorbents for wastewater treatment.

This study found that shallot (Allium ascalonicum) extracts reduced oxidative stress in human nasal epithelial cells caused by PAH exposure by decreasing ROS generation, suppressing lipid peroxidation, and restoring SOD activity, with quercetin being a key antioxidant component.

This review discusses the potential of using Arabidopsis thaliana to express fusion protein TDP1-KGF-2, aiming to enhance the transdermal delivery of KGF-2 for hair growth applications, despite current challenges with production costs and efficacy.

This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.

This review discusses the potential of natural products to induce ferroptosis as a promising therapeutic strategy for non-small cell lung cancer and reports no clinical results; the authors highlight the need for further comprehensive studies.

This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.

This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.

Ent-kaurane-type diterpenoids from Isodonis Herba may promote hair growth by boosting cell proliferation.

This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.

This review examines the anti-alopecia effects of plant-derived phytochemicals and their mechanisms for promoting hair growth, but it reports no new clinical findings.

This study found that Nelumbinis Semen extract may promote hair growth and reduce hair loss by increasing VEGF and IGF-1 expression and decreasing TGF-β1 in human dermal papilla cells and mice.

This study examined the effects of WNT10B on dermal papilla cells in vitro, finding that it alters gene expression, decreases protein synthesis, and upregulates a specific signaling pathway, potentially influencing hair follicle morphogenesis.

This study found that pretreatment with KP-Cryst fusion proteins effectively protected Asian and Caucasian virgin hair from thermal damage by maintaining higher water content and preventing structural changes during heat application.

This review highlights the challenges in developing nano-scale drug delivery systems for natural antioxidants in wound healing, pointing out issues like low solubility and skin permeability, and discusses potential solutions such as combining polymers and lipids to enhance delivery effectiveness.

This study demonstrated that α-phellandrene promotes dermal papilla cell proliferation through a cAMP-mediated pathway and upregulates VEGF expression, suggesting its potential use in hair loss prevention.

This review examines physical methods like electron paramagnetic resonance spectroscopy, Raman spectroscopy, and differential scanning calorimetry, highlighting their complementary capabilities in analyzing biomolecular structures and mycobacterial interactions with reactive oxygen species and antioxidants.

This study successfully optimized a culture strategy for dermal papilla cells and established an immortalized cell strain, iDP6, which is suitable for research and application.

This study reviews the potential of antioxidant plant compounds in improving wound healing for diabetic patients by reducing oxidative stress, controlling bacterial infections, and modulating inflammation, thereby promoting tissue regeneration and addressing key challenges in diabetic wound care.

This study suggests that phytochemicals from natural sources could be safer alternatives to conventional treatments for hair loss, as they may activate key pathways involved in hair growth.

In this literature review, researchers identified 68 African plants used in hair treatment, noting that 58 of these may also help with glucose metabolism issues, suggesting a nutritional therapy approach might explain their benefits.

This study explored using tyrosine as a cross-linking agent for curling Asian hair and found that it could shape hair effectively before washing without damaging the fibers, though the method was less effective after washing compared to commercial products.

This review describes various in vitro and ex vivo hair follicle models used to study hair growth and regeneration and explores their potential for developing hair loss treatments, but it does not report new results.

In this review, the authors discuss caffeine's potential mechanisms and benefits as a hair loss treatment, noting its possible effectiveness and safety, though they caution that existing studies often have significant design flaws.

In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.

In this study, researchers observed that Indian head cactus extract significantly increased the proliferation of human follicle dermal papilla cells and induced the expression of hair growth-related genes, suggesting its potential as a new therapy for promoting hair growth.

This review discusses the role of the Wnt/β-catenin pathway in hair follicle development and how natural products that activate this signaling could be used to treat hair loss, but it reports no new experimental results.