Potential of Nano-Encapsulation of Antioxidant Molecules in Wound Healing Applications: An Innovative Strategy to Enhance the Bio-Profile

This review explores the challenges and potential of nano-encapsulation of antioxidant molecules for wound healing applications. It highlights the difficulties in developing lipid and polymer-based drug delivery systems due to the antioxidants' low molecular weight, poor solubility, and inadequate skin permeability. The review suggests that combining polymers and lipids could enhance skin permeability. However, the lack of effective physical characterization techniques and scaling-up challenges limit the practical application of these nano-carriers. The review also discusses progressive strategies to overcome these obstacles and improve the bio-profile of antioxidant molecules in wound healing.