Nanotechnological Interventions and Mechanistic Insights into Wound-Healing Events

The document discussed the role of nanotechnology in enhancing wound-healing processes, particularly for chronic and burn wounds, by developing nanoparticle-based drug delivery systems that improve the efficacy of antimicrobial and bioactive agents. Despite advancements, the translation into commercially available products was limited. The wound-healing process involved phases of inflammation, proliferation, and remodeling, with nanotechnology-based therapies showing promise in enhancing these stages. Various nanomaterials, including metallic nanoparticles, polymeric nanostructures, and carbon-based materials, demonstrated potential in improving wound healing through antimicrobial activity and tissue regeneration. Liposomal systems and engineered scaffolds were explored for their ability to enhance therapeutic delivery and wound repair. Challenges remained in understanding the complex wound healing process and ensuring the biocompatibility and safety of nanomaterials, with future advancements expected to involve multifunctional nanotechnologies and personalized treatment plans.