Lipid Nanoparticles Based Cosmetics With Potential Application In Alleviating Skin Disorders

September 2021 in “ Cosmetics ”

Javed Ahmad

lipid nanoparticles solid lipid nanoparticles nanostructured lipid carriers minoxidil acne psoriasis atopic dermatitis hair loss natural antioxidants bio-cosmo-therapy SLN NLC

Studysummary This review discusses lipid nanoparticle-based cosmetics, emphasizing their potential in protecting skin from radiation and treating conditions like atopic dermatitis and psoriasis with synthetic and natural antioxidants. It highlights recent research on these formulations' effectiveness in alleviating skin disorders and enhancing skin health. Our plain-language summary of this paper — not a Tressless recommendation.

The review discussed the potential of lipid nanoparticles, specifically solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), in cosmetics for alleviating skin disorders such as acne, psoriasis, atopic dermatitis, and hair loss. These nanoparticles enhanced the delivery and efficacy of active ingredients, offering benefits like improved skin penetration, targeted release, and biocompatibility. For hair loss, minoxidil-encapsulated NLCs and SLNs provided a safer alternative to traditional formulations. The study emphasized the use of natural antioxidants and bio-cosmo-therapy to improve skin health and reduce side effects, highlighting the significant promise of lipid nanoparticles in developing advanced cosmetic products with therapeutic and beautifying effects.

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Research cited in this study

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research Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route

95 citations , July 2015 in “European journal of pharmaceutics and biopharmaceutics”

This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.

research Solid Lipid Nanoparticles Suspension Versus Commercial Solutions for Dermal Delivery of Minoxidil

26 citations , June 2011 in “International Journal of Pharmaceutics”

This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.

research Minoxidil-Loaded Nanostructured Lipid Carriers: Characterization and Rheological Behavior of Topical Formulations

46 citations , March 2009 in “Die Pharmazie”

This study describes the development of nanostructured lipid carriers for minoxidil as a potential alternative to conventional topical solutions, showing promise for use in topical formulations.