research Immunoregulatory Mechanisms and Stress Hormones in Psoriasis (Part 1)
Stress hormones like cortisol may trigger psoriasis flare-ups.
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research What Causes Hidradenitis Suppurativa?—15 Years After
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications
Alopecia areata severity and treatment response are linked to specific cytokine levels.
research The Impact of SARS-CoV-2 and COVID-19 on Male Reproduction and Men's Health
COVID-19 might affect male fertility, but more research is needed to understand the full impact.
research Novel and Established Potassium Channel Openers Stimulate Hair Growth In Vitro: Implications for Their Modes of Action in Hair Follicles
Potassium channel openers like minoxidil help hair grow by acting on hair follicles.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research A Humanized Mouse Model of Hereditary 1,25-Dihydroxyvitamin D–Resistant Rickets Without Alopecia
Researchers created a mouse model of a type of rickets that does not cause hair loss.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Teriflunomide in Multiple Sclerosis: An Update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research 25 Years of Estrogen Receptor Beta: A Personal Journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Overexpression of Hypoxia-Inducible Factor-1α in Hidradenitis Suppurativa: The Link Between Deviated Immunity and Metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
research Trichodysplasia of Immunosuppression Treated with Oral Valganciclovir
Oral valganciclovir improved a patient's skin condition caused by immunosuppression.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Signal Transducer and Activator of Transcription 5B Deficiency Due to a Novel Missense Mutation in the Coiled-Coil Domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research Immunomodulators in the Treatment of Cutaneous Lymphoma
Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.
research Alopecia Universalis After Alemtuzumab Treatment for Multiple Sclerosis: A Two-Year Follow-Up of Two Patients
Two patients developed complete hair loss after Alemtuzumab treatment for MS, with no regrowth after two years.
research Role of the Wnt Signaling Pathway in Keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
research Helminth Protein Enhances Wound Healing by Inhibiting Fibrosis and Promoting Tissue Regeneration
Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.
research Identification of Ferroptosis-Related Biomarkers in Alopecia Areata Through Machine Learning
Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.
research ATP-Dependent Chromatin Remodeling During Mammalian Development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Alopecia Areata: A Comprehensive Review of Pathogenesis and Management
New treatments for Alopecia Areata show promise but need to be more effective and affordable.
research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function
A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
research Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
research Skin Manifestations in Primary Immunodeficient Children
Nearly half of children with primary immunodeficiency disorders showed skin problems, often as the first sign of their condition.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research To Grow or Not to Grow: Hair Morphogenesis and Human Genetic Hair Disorders
Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
research Identifying Key Components and Therapeutic Targets of the Immune System in Hidradenitis Suppurativa with an Emphasis on Neutrophils
The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
research Wnt Signaling Activation: Targets and Therapeutic Opportunities for Stem Cell Therapy and Regenerative Medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research The Possible Implication of the S250C Variant of the Autoimmune Regulator Protein in a Patient with Autoimmunity and Immunodeficiency: In Silico Analysis Suggests a Molecular Pathogenic Mechanism for the Variant
The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.