35 citations,
May 2012 in “Expert Opinion on Pharmacotherapy” The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.
39 citations,
June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” Plant-based ingredients are effective and safe for modern skincare products.
25 citations,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
20 citations,
December 2013 in “Journal of Dermatology” UV-B light increases inflammation-related substances in acne-related skin cells.
20 citations,
October 2013 in “British Journal of Dermatology” The document concludes that clinicians should be aware of common hair and scalp disorders in women of African descent and that more research is needed to develop effective treatments.
16 citations,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
15 citations,
March 2014 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.
6 citations,
January 2021 in “International Journal of Molecular Sciences” Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
January 2011 in “Springer eBooks” Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.
5 citations,
February 2017 in “Biomolecules & Therapeutics” 4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.
8 citations,
October 2021 in “Microbiology spectrum” Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
6 citations,
August 2020 in “Cell regeneration” Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.
1 citations,
December 2023 in “Biomolecules” Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
May 2024 in “Journal of functional foods” Coffee bean residue extract helps hair growth by activating cell processes.
October 2023 in “Benha Journal of Applied Sciences” PPAR-γ may be a key target for treating alopecia areata and other skin conditions.
46 citations,
April 2008 in “Archives of Dermatological Research” Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
July 2018 in “Elsevier eBooks” Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
7 citations,
June 2021 in “Trends in Food Science and Technology” Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
295 citations,
September 2006 in “Cell Cycle” The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
107 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
91 citations,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
82 citations,
October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
75 citations,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
66 citations,
March 2018 in “British journal of dermatology/British journal of dermatology, Supplement” An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
57 citations,
February 2014 in “Experimental Dermatology” Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
40 citations,
March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
27 citations,
February 2020 in “Journal of Cardiovascular Translational Research” Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
25 citations,
March 2018 in “Clinics in Dermatology” Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.