Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia

November 2023 in “ bioRxiv (Cold Spring Harbor Laboratory) ”

Leemon Nikhila, Surya Suresh, Shahul Hameed Najeeb, Thankachan Mangalathettu Binumon, Aayush Gupta, Sandeep Gopalakrishnan, Parameswara Panicker Sreejith

Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

Studysummary This study found that disrupted cholesterol homeostasis impairs hair regrowth in individuals with primary cicatricial alopecia by damaging hair follicle stem cells, highlighting the importance of cholesterol in maintaining stem cell function and hair follicle integrity.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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