Hair Follicle-Related MicroRNA-34a Serum Expression and rs2666433A/G Variant in Patients with Alopecia: A Cross-Sectional Analysis

    April 2022 in “ Biomolecules ”
    Shymaa Ahmed Maher, Nader Ismail, Eman A. Toraih … Ghada M. Helal
    Studysummary This study found that the MIR34A rs2666433 (A/G) variant is linked to increased risk and severity of alopecia areata, and high circulatory miR-34a levels may play a role in the disease's pathogenesis.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 27

    1. Histone Deacetylase 1 in Patients With Alopecia Areata and Acne Vulgaris: An Epigenetic Alteration Australasian Journal of Dermatology · 2022
    2. The Potential Role of hsa_circ_0001079 in Androgenetic Alopecia via Sponging hsa-miR-136-5p Journal of Clinical Laboratory Analysis · 2021
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    7. Defining MicroRNA Signatures of Hair Follicular Stem and Progenitor Cells in Healthy and Androgenic Alopecia Patients Journal of Dermatological Science · 2020
    8. Association of Rs231775 Genetic Variant of Cytotoxic T-Lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case-Control Study Immunological Investigations · 2020
    9. PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology Experimental Dermatology · 2019
    10. Association of Autoimmune Regulator Gene Rs2075876 Variant, but Not Gene Expression, with Alopecia Areata in Males: A Case-Control Study Immunological investigations · 2019
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    12. Identification of Blood MicroRNA Alterations in Patients With Severe Active Alopecia Areata Journal of Cellular Biochemistry · 2019
    13. Genetic Analysis of a Novel Antioxidant Multi-Target Iron Chelator, M30, Protecting Against Chemotherapy-Induced Alopecia in Mice BMC cancer · 2019
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    15. Adipose and Hair Function: An Apparent Connection Journal of Investigative Dermatology · 2018
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    17. Epithelial-To-Mesenchymal Stem Cell Transition In A Human Organ: Lessons From Lichen Planopilaris Journal of Investigative Dermatology · 2017
    18. Identification of Differentially Expressed miRNAs in Alopecia Areata That Target Immune-Regulatory Pathways Genes and immunity · 2017
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    20. The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology Experimental Dermatology · 2015
    21. MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway Journal of Cell Biology · 2014
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    23. Alopecia Areata: A Possible Extraintestinal Manifestation of Crohn's Disease Journal of Crohn's and colitis · 2012
    24. Inducible Deletion of Epidermal Dicer and Drosha Reveals Multiple Functions for miRNAs in Postnatal Skin Development · 2012
    25. MicroRNAs Take Part in Pathophysiology and Pathogenesis of Male Pattern Baldness Molecular Biology Reports · 2009
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