Genetic Analysis of a Novel Antioxidant Multi-Target Iron Chelator, M30, Protecting Against Chemotherapy-Induced Alopecia in Mice

    February 2019 in “ BMC cancer ”
    Young-Cheol Lim, Il Tae Kim, Sang Moo Lim, Jin Su Kim
    Studysummary This study found that M30 may protect against cyclophosphamide-induced alopecia in mice by enhancing hair growth and preventing abnormal hair, suggesting its potential as a treatment.
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    Research cited in this study 9

    1. Testing Chemotherapeutic Agents in the Feather Follicle Identifies a Selective Blockade of Cell Proliferation and a Key Role for Sonic Hedgehog Signaling in Chemotherapy-Induced Tissue Damage Journal of Investigative Dermatology · 2014
    2. Treatment of Chemotherapy-Induced Alopecia Dermatologic Therapy · 2011
    3. Protection Against Chemotherapy-Induced Alopecia Pharmaceutical Research · 2006
    4. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005
    5. Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression The FASEB Journal · 2003
    6. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    7. Reduction of Intrafollicular Apoptosis in Chemotherapy-Induced Alopecia by Topical Calcitriol Analogs ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    8. Protection Against Cytosine Arabinoside-Induced Alopecia by Minoxidil in a Rat Animal Model International Journal of Dermatology · 1995
    9. Treatment with ImuVert and N-Acetylcysteine Protects Rats from Cyclophosphamide and Cytarabine-Induced Alopecia Cancer investigation · 1992

    Related research 6

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    2. Hair Loss: Causes and Pathology International Journal of Research in Medical Sciences & Technology · 2021
    3. Diffuse Hair Loss Elsevier eBooks · 2021
    4. Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle Trends in pharmacological sciences · 2013
    5. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    6. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001