ER71/ETV2 Promotes Hair Regeneration from Chemotherapy-Induced Hair Loss by Enhancing Angiogenesis

    April 2021 in “ Biomolecules & Therapeutics ”
    Tae-Jin Lee, Hee‐Kyoung Kang, Jeffrey C. Berry … Kyunghee Choi
    Studysummary In a mouse model of chemotherapy-induced alopecia, this study found that enhancing ETV2 expression improved angiogenesis and hair regrowth following 5-fluorouracil treatment.
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    Research cited in this study 13

    1. Prevention and Treatment of Chemotherapy-Induced Alopecia Dermatology practical & conceptual · 2020
    2. Pathogenesis and Treatment Options for Chemotherapy-Induced Alopecia: A Systematic Review International Journal of Dermatology · 2018
    3. Platelet-Rich Plasma Stimulates Angiogenesis in Mice Which May Promote Hair Growth European Journal of Medical Research · 2017
    4. A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention Oncologist · 2017
    5. Perivascular Hair Follicle Stem Cells Associate With a Venule Annulus Journal of Investigative Dermatology · 2013
    6. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    7. Treatment of Chemotherapy-Induced Alopecia Dermatologic Therapy · 2011
    8. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    9. Chemotherapy Targets the Hair Follicle Vascular Network but Not the Stem Cells Journal of Investigative Dermatology · 2006
    10. Promoted Growth of Murine Hair Follicles Through Controlled Release of Vascular Endothelial Growth Factor Biomaterials · 2002
    11. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    12. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    13. Expression of Vascular Endothelial Growth Factor (VEGF) in Various Compartments of the Human Hair Follicle Archives of Dermatological Research · 1998

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    4. Alopecia Areata: A Non-Scarring, Multifocal Hair Growth Disorder Harper's Textbook of Pediatric Dermatology · 2011
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    7. PUVA Therapy for Alopecia Areata 1981