The Potential Role of hsa_circ_0001079 in Androgenetic Alopecia via Sponging hsa-miR-136-5p

    November 2021 in “ Journal of Clinical Laboratory Analysis ”
    Hanxiao Wei, Xiao-Yu Xu, Jiaying Liu, Chang Liu, Qiang Li, Peisheng Jin
    TLDR hsa_circ_0001079 may help diagnose and treat hair loss.
    This study explores the role of circular RNA hsa_circ_0001079 in androgenetic alopecia (AGA) by analyzing hair follicles from 30 AGA patients and 30 healthy individuals. The findings indicate that hsa_circ_0001079 is significantly upregulated in AGA patients, suggesting its potential as a diagnostic marker. The study highlights the interaction between hsa_circ_0001079 and hsa-miR-136-5p, which may regulate hair follicle cell functions and influence hair growth by affecting the Wnt signaling pathway and DNA replication processes. The research suggests that hsa_circ_0001079 could serve as a novel diagnostic marker and therapeutic target for AGA, although further studies with larger sample sizes are needed.
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