Current Progress on Cordyceps Militaris, Its Metabolite Function, and Production

    May 2024 in “ Applied Sciences
    Yu-Chieh Chou, Ting-Hsuan Sung, Shi-Jing Hou, Darin Khumsupan, Shella Permatasari Santoso, Kuan‐Chen Cheng, Shin‐Ping Lin
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    Studysummary This review analyzed current studies on metabolite production from the medicinal fungus Cordyceps militaris, focusing on its fermentation modes and biological functions, and emphasizes the need for modern fermentation processes to enhance industrial production. Our plain-language summary of this paper — not a Tressless recommendation.
    Cordyceps militaris is a medicinal fungus recognized for its bioactive compounds, including cordycepin, D-mannitol, ergothioneine, adenosine, and polysaccharides, which offer antioxidant, anti-inflammatory, antiviral, antitumor, and anti-hair loss benefits. The document reviews the production methods of these metabolites, emphasizing the advantages of liquid culture and repeated-batch fermentation for efficient and scalable production. It highlights the potential of C. militaris as a cost-effective alternative to C. sinensis in traditional medicine, with improved yields through optimized fermentation processes and UV-induced mutations.
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