Adipose-Derived Stem/Stromal Cells in Regenerative Medicine

    January 2016 in “ Springer eBooks ”
    Jie Li, Elizabeth C. Martin, Jeffrey M. Gimble
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    TLDR Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
    The document from 2016 highlights the potential of adipose-derived stem/stromal cells (ASCs) in regenerative medicine, noting their multipotency and ability to differentiate into various cell lineages, including those relevant for treating alopecia, liver damage, bone defects, and nerve injuries. It reports that 168 clinical trials involving ASCs were registered, with 38 completed, and discusses various preconditioning strategies to enhance ASCs' therapeutic effects. The document also stresses the importance of Good Manufacturing Practice standards and the need for further research on the safety, effectiveness, and long-term outcomes of ASC therapies.
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