research Oral Dutasteride Is a First-Line Treatment for Frontal Fibrosing Alopecia
Oral dutasteride is effective and safe for treating frontal fibrosing alopecia.
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150-180 / 470 results research Roles of MED1 in Quiescence of Hair Follicle Stem Cells and Maintenance of Normal Hair Cycling
MED1 is essential for normal hair growth and maintaining hair follicle stem cells.
research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations
Deleting MED1 in skin cells causes hair loss and skin changes.
research Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness?
Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
research Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation
A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
research Stem Cells and the Circadian Clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Saw Palmetto Extract: A Dermatologist's Perspective
Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.
research Role of Stem/Progenitor Cells in Reparative Disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Pathological Sequelae of Long-Haul COVID
Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.
research Development and Homeostasis of the Sebaceous Gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research 5-Bromo-2′-Deoxyuridine Induced Effluvium via p53-Mediated CD326-Positive Keratinocyte Apoptosis in C57BL/6 Mice
A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.
research Genetics and Epigenetics of Polycystic Ovary Syndrome
Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.
research Regulatory T Cells: The Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
research Blimp1+ Cells Generate Functional Mouse Sebaceous Gland Organoids In Vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research Gender Differences in Cardiac Hypertrophy
Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
research 15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth
A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.
research The Role of Lysophosphatidic Acid in the Physiology and Pathology of the Skin
Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
research Regulation of Adipocyte Dedifferentiation at the Skin Wound Edge
Adipocytes can change into fibroblast-like cells to help with wound healing.
research Genotyping Of The Rs1800440 Polymorphism In CYP1B1 Gene And The Rs9258883 Polymorphism In HLA-B Gene In A Spanish Cohort Of 223 Patients With Frontal Fibrosing Alopecia
Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.
research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
research Lipin 1 Gene Polymorphisms in Polycystic Ovary Syndrome
Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.
research Platelet-Rich Plasma: Applications in Cosmetic Medicine and Surgery
PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.
research Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research MTOR Signaling in Hair Follicle and Hair Diseases: Recent Progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research A Guide to Studying Human Dermal Adipocytes In Situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research Medicinal Plants with Traditional Use: Ethnobotany in the Indian Subcontinent
Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.
research The Role of Leptin in Selected Skin Diseases
Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
research Pregnancy in Postpartum Estrus Induces Inflammatory Milk Production and Catagen-Specific Pup Skin Inflammation in Interleukin-10 Deficient Mice
Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.