Platelet-Rich Plasma: Applications in Cosmetic Medicine and Surgery

The document from June 1, 2018, provides an overview of Platelet-Rich Plasma (PRP) and its applications in cosmetic medicine and surgery, including its potential for promoting hair growth and skin rejuvenation. It highlights the presence of growth factors in PRP that can stimulate hair growth, referencing studies such as Uebel et al. (2006) and Alves and Grimalt (2013), which showed positive effects on hair follicular unit density and hair volume and density, respectively. However, the evidence is inconsistent, and there is a lack of standardization in PRP preparation. For skin rejuvenation, while animal studies have shown positive effects, clinical evidence in humans is mixed, with some studies reporting improvements and others showing no significant difference. The document concludes that more rigorous studies are needed to confirm PRP's effectiveness in these applications due to variability in preparation protocols and a lack of high-quality evidence.